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We observed that GLP-1 increased MAP and HR in both HF and Sham rats

64 In serine proteases, neutrophil elastase (NE), cathepsin G and proteinase-3 destroy lung tissue by degrading ECM components, and induces epithelial cells and endothelial cells to release a variety of inflammatory factors to activate and chemoattract neutrophils to produce lung inflammation

Excretion occurred primarily via urine and bile

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